Bradykinin is a nonapeptide (9 amino acids) derived from kininogens by kallikrein enzymes, acting as a key mediator in the kinin-kallikrein system. It binds to B1 and B2 receptors, triggering vasodilation, increased vascular permeability, smooth muscle contraction, and pain sensation, playing critical roles in inflammation, tissue repair, and cardiovascular regulation. In pharmacological research, Bradykinin serves as a tool to investigate inflammatory signaling, nociception, and endothelial function, while also contributing to the development of therapies for conditions like hypertension, asthma, and chronic pain. Its short half-life and susceptibility to degradation highlight its role in acute physiological responses, underscoring its significance in both basic science and translational medicine.

Chemical Formula: C50H73N15O11

Molecular Weight: 2957.40

Sequence: Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg

Purity: From crude to 98%

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Research Use Only