Biotin-Bradykinin is a synthetic analog of the endogenous nonapeptide Bradykinin, incorporating a biotin tag for detection, purification, or immobilization in biochemical studies. This modification preserves Bradykinin’s bioactivity, allowing it to bind B1 and B2 receptors to mediate vasodilation, vascular permeability, smooth muscle contraction, and pain signaling. In pharmacological research, it serves as a tool to investigate inflammatory pathways, nociception, and endothelial function, while enabling receptor-binding studies and drug discovery for conditions like hypertension, asthma, and chronic pain. The biotinylation enhances its utility in affinity chromatography, imaging, and proteomics, supporting mechanistic insights into Bradykinin signaling and therapeutic development.

Chemical Formula: C60H87N17O13S

Molecular Weight: 1286.53

Sequence: Biotin-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg

Purity: From crude to 98%

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Research Use Only