$452.00 - $452.00
Pentagastrin is a compact synthetic gastrin-related ligand built around the receptor-active C-terminal region of gastrin.
Its structure, Boc-β-Ala-Trp-Met-Asp-Phe-NH₂, retains the principal C-terminal gastrin pharmacophore while providing a smaller experimental ligand than endogenous Gastrin-17.
Product Information
| Property | Specification |
|---|---|
| Product Name | Pentagastrin |
| Catalog No. | AS2719 |
| Sequence | Boc-β-Ala-Trp-Met-Asp-Phe-NH₂ |
| Molecular Weight | Approximately 768.8 Da |
| C-Terminus | Amide |
| Peptide Class | Synthetic gastrin analog |
| Primary Target | CCK2R / CCKBR |
| Purity | Crude to 98% |
Molecular Design
Pentagastrin retains the Trp-Met-Asp-Phe-NH₂ sequence associated with gastrin receptor activation and includes an N-terminal Boc-β-Ala element.
The Boc group and β-alanine residue are part of the defined molecule. Pentagastrin should therefore be identified by its complete chemical structure when compared with native gastrins or truncated gastrin peptides.
Research Applications
Pentagastrin is useful in CCK2R activation assays, gastric signaling studies and experiments examining how peptide length and terminal structure influence gastrin receptor pharmacology.
Related native and modified ligands are available in the Gastrin, GRP & Bombesin Peptides collection.
Experimental Planning
For receptor-focused work, the complete molecular form and C-terminal amide should be confirmed together with purity. Researchers planning sensitive assays can review our Recommended Peptide Purity guidance.
Frequently Asked Questions
Is Pentagastrin a naturally occurring gastrin peptide?
No. Pentagastrin is a synthetic gastrin-related ligand rather than a native circulating gastrin form.
Can Pentagastrin analogs be synthesized?
Sequence substitutions and alternative terminal structures can be evaluated through Chemical Peptide Synthesis.