$6203.00 - $18609.00
N-Ac-L-Trp-n-propylamide, also written Ace-Trp-N(n-Pr), is a terminally capped L-tryptophan model compound with an N-acetyl group and an n-propylamide terminus. Blocking both termini reduces ionic end-group effects and creates a compact system for studying local backbone behavior around tryptophan.
The compound has been used in VCD, IR, solvation and molecular-dynamics studies of tryptophan-containing peptide models. Its main value is as a defined conformational and chiroptical research material rather than an elongatable peptide building block.
Product Information
| Product Name | N-Ac-L-Trp-n-propylamide |
| Common Notation | Ace-Trp-N(n-Pr) |
| Catalog No. | AS4041 |
| CAS No. | No reliable public CAS assignment confirmed |
| Molecular Formula | C16H21N3O2 |
| Molecular Weight | 287.36 g/mol |
| Primary Use | Peptide conformational and chiroptical model studies |
Conformational and Solvation Research
The indole side chain provides an aromatic hydrogen-bond donor and hydrophobic surface, while the capped backbone minimizes terminal charge. This makes Ace-Trp-N(n-Pr) useful for comparing solvent-dependent conformational ensembles and self-association in simplified peptide systems.
Analytical Fit and Lot Documentation
For spectroscopy or computational benchmarking, confirm L-tryptophan stereochemistry, terminal capping and lot-specific purity. When no unique CAS is available, structural documentation and Catalog No. AS4041 become especially important for identity control.
Concentration and solvent can influence association and spectroscopic response. Prepare solutions under controlled conditions and document solvent history when comparing datasets.
Related model compounds can be reviewed in analytical research compounds.
Product Documents
MSDS - N-Ac-L-Trp-n-propylamide (AS4041)
The Safety Data Sheet provides product identification, laboratory handling guidance, exposure controls, transport information and safety information for research use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
Is this an SPPS building block?
Not in the conventional sense. Both termini are capped, so its main use is as a defined model compound.
Why is solvent control important?
Solvation and concentration can change the conformational ensemble and degree of self-association measured in spectroscopy or simulation studies.