Magainin 1 is a 23 - amino - acid antimicrobial peptide originally isolated from the skin of the African clawed frog (Xenopus laevis). It has an amphipathic structure with a helical conformation that allows it to interact with and disrupt the membranes of various pathogens. Magainin 1 shows broad - spectrum activity against bacteria, fungi, and some enveloped viruses. It works by inserting into the lipid bilayer of the target cell membrane, creating pores that lead to the leakage of intracellular contents and ultimately cell death. In pharmacological research, it serves as a model compound for understanding the mechanisms of antimicrobial peptides and for developing novel anti - infectious agents, especially in the face of growing antibiotic resistance.

Chemical Formula: C112H177N29O28S

Molecular Weight: 2409.90

Sequence: Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Gly-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Lys-Ser

Purity: From crude to 98%

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Research Use Only