$482.00 - $482.00
Gastrin Releasing Peptide Lys(Biotin), human is a modified GRP-derived construct containing a Lys-linked biotin group.
The biotin moiety provides an affinity handle for streptavidin-based detection and capture while retaining a GRP-derived peptide backbone for receptor-interaction studies.
Product Information
| Property | Specification |
|---|---|
| Product Name | Gastrin Releasing Peptide Lys(Biotin), Human |
| Catalog No. | AS2680 |
| Listed Sequence | Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-Lys(Biotin) |
| Modification | Lys-linked biotin |
| Peptide Family | Gastrin-releasing peptide |
| Research Target | GRPR / BB2 |
| Purity | Crude to 98% |
Biotin Placement and Molecular Design
GRP receptor recognition is strongly influenced by the C-terminal region. Addition of Lys(Biotin) adjacent to this region changes the molecular architecture and can influence receptor interaction, steric accessibility and assay response.
We recommend treating biotin position as part of the experimental specification, particularly in quantitative binding or signaling studies.
Research Applications
This construct can support streptavidin capture, peptide–receptor interaction studies and development of labeled GRP assay systems.
Related native and modified GRP peptides are available in the Gastrin, GRP & Bombesin Peptides collection.
Frequently Asked Questions
Is GRP Lys(Biotin) equivalent to native human GRP?
No. The additional biotinylated lysine changes the terminal structure and molecular properties of the peptide.
Can alternative biotin positions or spacers be used?
Alternative biotinylation positions, Ahx spacers and related conjugation designs can be evaluated through Chemical Peptide Synthesis.