$482.00 - $482.00
Biotin-Gastrin Releasing Peptide, human is an N-terminally biotinylated form of human GRP-27.
The construct provides a biotin affinity handle while retaining the native amidated C-terminal GRP region associated with receptor interaction.
Product Information
| Property | Specification |
|---|---|
| Product Name | Biotin-Gastrin Releasing Peptide, Human |
| Catalog No. | AS2628 |
| Sequence | Biotin-Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH₂ |
| Peptide Length | 27 amino acids |
| Molecular Weight | Approximately 3085.7 Da |
| Modification | N-terminal biotin |
| C-Terminus | Amide |
| Primary Target | GRPR / BB2 |
| Purity | Crude to 98% |
N-Terminal Biotinylation
Positioning biotin at the N-terminus preserves the native C-terminal sequence architecture of GRP.
This configuration can support affinity capture, streptavidin detection and ligand–receptor interaction workflows. The label still changes molecular mass and the physicochemical environment of the peptide.
We recommend including native GRP as a reference when quantitative receptor affinity or signaling is an experimental endpoint.
Research Applications
Biotin-GRP can support receptor interaction studies, streptavidin-based capture, assay development and peptide detection workflows.
Frequently Asked Questions
Is Biotin-GRP chemically identical to native GRP?
No. N-terminal biotinylation changes molecular mass and the N-terminal chemical environment.
Can a spacer be incorporated between biotin and GRP?
Spacer-containing constructs and alternative label positions can be evaluated through Chemical Peptide Synthesis.