Gastrin I (rat) is a peptide hormone produced by gastric G cells in rats, playing a key role in regulating gastric acid secretion, stimulating the growth of gastric mucosal cells, and influencing gastrointestinal motility. Structurally similar to its human counterpart, this hormone binds to cholecystokinin B receptors (CCKBR) on parietal and enteroendocrine cells, triggering signaling pathways that enhance acid production and modulate digestive functions. Gastrin I (rat) is used in research to study gastrointestinal physiology, receptor-ligand interactions, and the mechanisms underlying acid-related disorders or mucosal hyperplasia. As a model for mammalian gastrin biology, it aids in understanding the regulation of gastric function and the effects of pharmacological interventions targeting gastrin signaling pathways.

Chemical Formula: C94H128N22O31S2

Molecular Weight: 2126.30

Sequence: Pyr-Arg-Pro-Pro-Met-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2

Purity: From crude to 98%

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Research Use Only