$1206.00 - $3618.00
Z-Tyr(tBu)-OMe (CAS 5068-29-1) is a Protected amino-acid / amino-ester intermediate used in solution-phase synthesis and protected amino-acid derivatization. Its main synthetic value is selective functionalization, ester chemistry and route development.
Check which functional group remains available before substituting it for a conventional SPPS monomer; protection pattern defines the usable reaction handle. Before substitution into an established synthesis, compare stereochemistry, protecting-group orthogonality and downstream deprotection requirements.
Product Information
| Product Name | Z-Tyr(tBu)-OMe |
| Catalog No. | AS4275 |
| CAS No. | 5068-29-1 |
| Molecular Formula | C22H27NO5 |
| Molecular Weight | 385.45 g/mol |
| Compound Type | Protected amino-acid / amino-ester intermediate |
| Primary Research Use | Solution-phase synthesis and protected amino-acid derivatization |
Protection Pattern and Synthetic Role
Z-Tyr(tBu)-OMe combines an amino-acid framework with selective protection or esterification. The practical role is determined by which amino, carboxyl or side-chain functions remain free for the next transformation.
Solution-Phase and Derivatization Use
Such intermediates are useful in stepwise small-molecule synthesis, protected peptide-fragment preparation and route development where orthogonality is more important than direct compatibility with a single standard SPPS cycle.
Selection Considerations
Do not substitute one protected amino-acid form for another based only on the parent residue name. The ester, N-protecting group, salt form and side-chain protection change reactivity and deprotection sequence.
Related options are grouped under unusual amino acid range. For broader route support, see advanced peptide building blocks.
Product Documents
MSDS - Z-Tyr(tBu)-OMe (AS4275)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Frequently Asked Questions
What is Z-Tyr(tBu)-OMe mainly used for?
Solution-phase synthesis and protected amino-acid derivatization.
What is the critical identity check?
Confirm CAS 5068-29-1, stereochemistry or positional isomer where applicable, and the complete protection state.
What documentation should be matched to the lot?
Use the COA to confirm assay and analytical identity; the nominal formula is C22H27NO5 with molecular weight 385.45 g/mol.