Kemptide is a synthetic peptide substrate widely used to study protein kinase C (PKC) activity, composed of the consensus PKC phosphorylation sequence (RRLSSLSLK). This peptide contains serine residues that serve as specific targets for PKC-mediated phosphorylation, making it a standard tool in biochemical assays to measure PKC enzymatic activity, screen for kinase inhibitors, or investigate PKC-dependent signaling pathways. Its core sequence mimics natural PKC substrates, enabling researchers to evaluate phosphorylation efficiency and downstream signaling events in cellular and cell-free systems. Kemptide’s role in elucidating PKC function makes it essential for understanding cellular signaling mechanisms and developing therapies targeting PKC-related pathways in diseases such as cancer and inflammation.

Chemical Formula: C32H61N13O9

Molecular Weight: 771.92

Sequence: Leu-Arg-Arg-Ala-Ser-Leu-Gly

Purity: From crude to 98%

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Research Use Only