Biotin-Kemptide is a synthetic peptide substrate designed for studying protein kinase C (PKC) activity, conjugating to biotin. The biotin moiety enables easy detection and purification of phosphorylated products through streptavidin-based affinity methods, while the core peptide sequence serves as a specific target for PKC-mediated phosphorylation at serine residues. This substrate is widely used in biochemical assays to measure PKC enzymatic activity, screen for kinase inhibitors, or investigate signaling pathways involving PKC. Its biotinylated form facilitates downstream applications such as pull-down assays, ELISA, or Western blot analysis, making it a versatile tool in cellular signaling research and drug discovery targeting PKC-dependent pathways.

Chemical Formula: C42H75N15O11S

Molecular Weight: 998.22

Sequence: Biotin-Leu-Arg-Arg-Ala-Ser-Leu-Gly

Purity: From crude to 98%

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Research Use Only