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H-Asp-Glu-OH; CAS 6157-06-8 is L-aspartyl-L-glutamic acid; Asp-Glu, an acidic dipeptide containing both aspartate and glutamate. Sequence order is part of the identity because Asp-Glu and Glu-Asp share the same elemental composition but are different molecules.
The compound is suited to analytical, metabolite and sequence-isomer comparison studies where retention, ionization or enzyme recognition may depend on residue order.
Product Information
| Product Name | H-Asp-Glu-OH |
| Catalog No. | AS4152 |
| CAS No. | 6157-06-8 |
| Molecular Formula | C9H14N2O7 |
| Molecular Weight | 262.22 g/mol |
| Sequence / Identity | Asp-Glu |
| Synonym | L-aspartyl-L-glutamic acid; Asp-Glu |
| Primary Research Use | acidic dipeptide reference |
Sequence-Order and Acidic Peptide Analysis
Asp-Glu and Glu-Asp are constitutional sequence isomers with the same formula and nominal mass. LC retention, fragmentation and enzyme recognition can differ, so sequence order must be confirmed rather than inferred from MS1 mass alone.
Analytical Identity and Method Development
Short peptides are often purchased as reference compounds because exact sequence, terminal state and stereochemistry can influence retention, ionization and fragmentation. When peak assignment matters, use the exact compound identity rather than relying only on nominal molecular mass.
Procurement and QC Considerations
For research use, match the requested purity and documentation to the experiment. Analytical or quantitative studies benefit from lot-specific HPLC and MS data, while metabolomics or sequence-isomer work may require additional identity controls.
For identity and purity documentation, review our peptide QC methods for HPLC and mass-spectrometric characterization principles.
For broader sequence or project work, see analytical peptide references.
Analytical Use and Lot Documentation
For qualitative identification or method development, sequence identity, expected molecular mass and chromatographic purity may be sufficient. Quantitative use can require additional lot-specific information such as an assigned purity or content basis and a preparation protocol appropriate to the analytical method.
HPLC purity and mass-spectrometric identity answer different questions and should not be treated as interchangeable. Solubility and solution stability should also be validated at the concentration and solvent conditions used in the experiment when no product-specific solution data are available.
Product Documents
The Safety Data Sheet provides product identification, laboratory handling guidance, exposure controls, transport information and safety information for research use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
What is H-Asp-Glu-OH?
It is L-aspartyl-L-glutamic acid; Asp-Glu, a defined research compound with sequence or structural identity Asp-Glu.
What is the main value of this product?
Its main value is as a chemically defined reference for acidic dipeptide reference.
What should be checked before quantitative use?
Confirm lot-specific identity, purity basis and analytical documentation appropriate to the method.