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Fmoc-Lys(ivDde)-OH (CAS 204777-78-6) belongs to the protected amino-acid / peptidomimetic building block class. It is used in peptide, peptidomimetic and medicinal-chemistry synthesis, particularly where a diamino-acid framework whose protecting-group pattern controls orthogonal side-chain functionalization is required.
Use when the target structure specifically requires this residue or protection pattern; confirm stereochemistry and deprotection compatibility before substituting it into an established route. Before substitution into an established synthesis, compare stereochemistry, protecting-group orthogonality and downstream deprotection requirements.
Product Information
| Product Name | Fmoc-Lys(ivDde)-OH |
| Catalog No. | AS4249 |
| CAS No. | 204777-78-6 |
| Molecular Formula | C34H42N2O6 |
| Molecular Weight | 574.71 g/mol |
| Compound Type | Protected amino-acid / peptidomimetic building block |
| Primary Research Use | Peptide, peptidomimetic and medicinal-chemistry synthesis |
Why This Building Block Is Distinct
The defining feature of Fmoc-Lys(ivDde)-OH is a diamino-acid framework whose protecting-group pattern controls orthogonal side-chain functionalization. That feature can change hydrophobic packing, conformational preference, side-chain reactivity or the route available for later derivatization.
Coupling and Deprotection Fit
Compatibility should be assessed against the full sequence and protection map. A chemically correct residue can still be a poor substitution if its protecting group is removed by conditions required elsewhere in the synthesis.
Compare neighboring reagents in our noncanonical amino acids. Full-sequence work is covered under protected peptide building blocks.
Product Documents
MSDS - Fmoc-Lys(ivDde)-OH (AS4249)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
Why does the exact derivative matter?
Fmoc-Lys(ivDde)-OH is selected for its defined functional groups and protection pattern; related forms can require different coupling or deprotection conditions.
Can a close analog replace Fmoc-Lys(ivDde)-OH?
Not safely by name alone. For Fmoc-Lys(ivDde)-OH, compare stereochemistry, protecting groups, salt/ester form and the intended downstream transformation.
What should procurement verify?
Match the product to CAS 204777-78-6 and the lot-specific COA rather than relying only on a shorthand chemical name.