$1033.00 - $3101.00
Fmoc-Asu(OtBu)-OH (CAS 276869-41-1) belongs to the protected amino-acid / peptidomimetic building block class. It is used in peptide, peptidomimetic and medicinal-chemistry synthesis, particularly where an acidic amino-acid derivative with ester protection used to control carboxyl-group reactivity is required.
Use when the target structure specifically requires this residue or protection pattern; confirm stereochemistry and deprotection compatibility before substituting it into an established route. Its value is route-specific, so selection should follow the intended transformation rather than the broad category label.
Product Information
| Product Name | Fmoc-Asu(OtBu)-OH |
| Catalog No. | AS4287 |
| CAS No. | 276869-41-1 |
| Molecular Formula | C27H33NO6 |
| Molecular Weight | 467.55 g/mol |
| Compound Type | Protected amino-acid / peptidomimetic building block |
| Primary Research Use | Peptide, peptidomimetic and medicinal-chemistry synthesis |
Why This Building Block Is Distinct
The defining feature of Fmoc-Asu(OtBu)-OH is an acidic amino-acid derivative with ester protection used to control carboxyl-group reactivity. That feature can change hydrophobic packing, conformational preference, side-chain reactivity or the route available for later derivatization.
Coupling and Deprotection Fit
Compatibility should be assessed against the full sequence and protection map. A chemically correct residue can still be a poor substitution if its protecting group is removed by conditions required elsewhere in the synthesis.
Compare neighboring reagents in our noncanonical amino acids. Full-sequence work is covered under protected peptide building blocks.
Product Documents
MSDS - Fmoc-Asu(OtBu)-OH (AS4287)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
Why does the exact derivative matter?
Fmoc-Asu(OtBu)-OH is selected for its defined functional groups and protection pattern; related forms can require different coupling or deprotection conditions.
Can a close analog replace Fmoc-Asu(OtBu)-OH?
Not safely by name alone. For Fmoc-Asu(OtBu)-OH, compare stereochemistry, protecting groups, salt/ester form and the intended downstream transformation.
What should procurement verify?
Match the product to CAS 276869-41-1 and the lot-specific COA rather than relying only on a shorthand chemical name.