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Fmoc-(2-aminomethylphenyl)acetic acid (CAS 882847-15-6) belongs to the protected amino-acid / peptidomimetic building block class. It is used in peptide, peptidomimetic and medicinal-chemistry synthesis, particularly where a noncanonical or specially protected residue used to expand peptide and small-molecule chemical space is required.
Use when the target structure specifically requires this residue or protection pattern; confirm stereochemistry and deprotection compatibility before substituting it into an established route. Procurement should match the exact CAS, protection state and lot-specific analytical specification to the intended route.
Product Information
| Product Name | Fmoc-(2-aminomethylphenyl)acetic acid |
| Catalog No. | AS4282 |
| CAS No. | 882847-15-6 |
| Molecular Formula | C24H21NO4 |
| Molecular Weight | 387.43 g/mol |
| Compound Type | Protected amino-acid / peptidomimetic building block |
| Primary Research Use | Peptide, peptidomimetic and medicinal-chemistry synthesis |
Why This Building Block Is Distinct
The defining feature of Fmoc-(2-aminomethylphenyl)acetic acid is a noncanonical or specially protected residue used to expand peptide and small-molecule chemical space. That feature can change hydrophobic packing, conformational preference, side-chain reactivity or the route available for later derivatization.
Coupling and Deprotection Fit
Compatibility should be assessed against the full sequence and protection map. A chemically correct residue can still be a poor substitution if its protecting group is removed by conditions required elsewhere in the synthesis.
Compare neighboring reagents in our noncanonical amino acids. Full-sequence work is covered under protected peptide building blocks.
Product Documents
MSDS - Fmoc-(2-aminomethylphenyl)acetic acid (AS4282)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
What distinguishes Fmoc-(2-aminomethylphenyl)acetic acid in synthesis?
Its intended role is peptide, peptidomimetic and medicinal-chemistry synthesis, with the exact residue or functional-group state defined by the product structure.
Why check the protection map for Fmoc-(2-aminomethylphenyl)acetic acid?
In Fmoc-(2-aminomethylphenyl)acetic acid, the protection state determines which functions remain reactive and which deprotection conditions can be used later in the route.