10.0% Off
$81.90 - $418.50
L-3-Pyrazolyl-Alanine (CAS 2734-48-7) is supplied as a Unprotected heteroaromatic amino-acid analog. In research synthesis, it is most relevant to noncanonical amino-acid and medicinal-chemistry research and SAR studies, reference chemistry and derivatization of an unusual aromatic residue.
Because the amino and carboxyl groups are not preprotected for Fmoc-SPPS, select a protection strategy that matches the intended synthetic route. Its value is route-specific, so selection should follow the intended transformation rather than the broad category label.
Product Information
| Product Name | L-3-Pyrazolyl-Alanine |
| Catalog No. | AS4261 |
| CAS No. | 2734-48-7 |
| Molecular Formula | C6H9N3O2 |
| Molecular Weight | 155.15 g/mol |
| Compound Type | Unprotected heteroaromatic amino-acid analog |
| Primary Research Use | Noncanonical amino-acid and medicinal-chemistry research |
Noncanonical Residue Chemistry
L-3-Pyrazolyl-Alanine introduces an unusual side chain into an amino-acid framework. It can support SAR work, reference chemistry and preparation of protected derivatives for peptide or medicinal-chemistry programs.
Protection Before Peptide Assembly
The amino and carboxyl functions are not supplied as a standard Fmoc/tBu SPPS building block. If the residue is intended for peptide synthesis, a protection strategy should be selected to match the coupling and deprotection sequence.
Identity and Stereochemistry
Procurement should confirm the stated stereochemistry together with CAS, formula and analytical specification. Noncanonical amino acids with similar aromatic substituents are not interchangeable.
Additional chemistry is available in the specialty amino acid set. For synthesis planning beyond the building block, see specialty SPPS building blocks.
Product Documents
MSDS - L-3-Pyrazolyl-Alanine (AS4261)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
What distinguishes L-3-Pyrazolyl-Alanine in synthesis?
Its intended role is noncanonical amino-acid and medicinal-chemistry research, with the exact residue or functional-group state defined by the product structure.
Why check the protection map for L-3-Pyrazolyl-Alanine?
In L-3-Pyrazolyl-Alanine, the protection state determines which functions remain reactive and which deprotection conditions can be used later in the route.