[Cys3, 6, Tyr8, Pro10]-Substance P is a modified analog of Substance P with substitutions at positions 3, 6, 8, and 10: cysteine residues replace native amino acids at positions 3 and 6, tyrosine is incorporated at position 8, and proline is substituted at position 10. These modifications enhance structural stability, receptor-binding specificity for neurokinin-1 (NK-1) receptors, and selectivity in modulating pain signaling, inflammatory responses, and immune functions. Utilized in pharmacological research, this analog aids in investigating structure-activity relationships and exploring therapeutic potential for pain management and inflammatory disorders.

Chemical Formula: C58H83N17O14S3

Molecular Weight: 1295.60

Sequence: Asp-Asp-Phe-Me-Phe-Gly-Leu-Met-NH2

Purity: From crude to 98%

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Research Use Only