Substance P (1-9) is an N-terminal fragment of the neuropeptide Substance P, retaining a portion of its structural and functional characteristics. This peptide segment is employed in research to explore the role of specific regions in mediating receptor binding, enzymatic processing, and downstream signaling. While it may exhibit reduced or altered bioactivity compared to the full-length peptide, it provides insights into the molecular mechanisms underlying pain modulation, neuroinflammation, and neurogenic responses. Studies utilizing this fragment contribute to the development of peptide-based therapeutics and enhance understanding of neuropeptide behavior in health and disease.

Chemical Formula: C52H77N15O12

Molecular Weight: 1104.30

Sequence: Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly

Purity: From crude to 98%

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Research Use Only