[Tyr0]-Neurokinin A is a modified analog of Neurokinin A with tyrosine (Tyr) substituted at position 0 (N-terminal), replacing the native histidine (His). This modification enhances stability, resistance to enzymatic degradation, and binding specificity for neurokinin-2 (NK-2) receptors. Retaining bioactivity, it modulates inflammatory responses, immune functions, and cardiovascular regulation. Utilized in pharmacological research, this analog serves as a tool to investigate structure-activity relationships, receptor activation mechanisms, and explore therapeutic potential for inflammatory disorders and cardiovascular diseases.

Chemical Formula: C59H89N15O16S

Molecular Weight: 1296.52

Sequence: Tyr-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2

Purity: From crude to 98%

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Research Use Only