Biotin-LC-Kemptide is a synthetic peptide substrate used to study protein kinase C (PKC) activity, featuring a biotin moiety linked via a long-chain (LC) spacer to the PKC consensus phosphorylation sequence. The LC linker enhances solubility and reduces steric hindrance between biotin and the peptide, facilitating efficient interaction with streptavidin-based detection or purification systems. The core Kemptide sequence contains serine residues that serve as specific targets for PKC-mediated phosphorylation. This substrate is ideal for biochemical assays to quantify PKC enzymatic activity, screen for kinase inhibitors, or explore PKC-dependent signaling pathways. Its biotinylated design enables easy downstream applications such as affinity pull-downs, ELISA, or Western blotting, making it a versatile tool in cellular signaling research and drug discovery.

Chemical Formula: C48H86N16O12S

Molecular Weight: 1111.39

Sequence: Biotin-LC-Leu-Arg-Arg-Ala-Ser-Leu-Gly

Purity: From crude to 98%

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