Biotin-Gastrin Releasing Peptide, human is a biotinylated synthetic peptide corresponding to the human gastrin-releasing peptide (GRP), a 27-amino acid neuropeptide that binds to gastrin-releasing peptide receptors (GRPR) involved in gastrointestinal regulation and cell proliferation. The biotin moiety enables sensitive detection and affinity-based purification through streptavidin interactions, while the GRP sequence retains high specificity for GRPR, which is often overexpressed in cancers like prostate, breast, and small-cell lung cancer. This conjugate is used in research for studying GRPR-mediated signaling, developing targeted imaging agents (e.g., PET/SPECT tracers), and facilitating drug delivery to GRPR-positive cells. Its utility spans basic receptor biology, molecular imaging, and the design of therapeutic strategies aimed at exploiting GRPR overexpression in disease.

Chemical Formula: C140H218N40O33S3

Molecular Weight: 3085.74

Sequence: Biotin-Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2

Purity: From crude to 98%

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Research Use Only