$422.00 - $422.00
α-Neo-Endorphin (1-7) is a seven-residue N-terminal fragment of α-Neoendorphin with the sequence Tyr-Gly-Gly-Phe-Leu-Arg-Lys.
The peptide retains the complete Leu-enkephalin motif together with Arg6-Lys7 but removes Tyr8-Pro9-Lys10 from the native decapeptide, producing a compact scaffold for truncation and receptor-address studies.
Product Information
| Property | Specification |
|---|---|
| Product Name | α-Neo-Endorphin (1-7) |
| Catalog No. | AS2588 |
| Sequence | Tyr-Gly-Gly-Phe-Leu-Arg-Lys |
| One-Letter Sequence | YGGFLRK |
| Peptide Length | 7 residues |
| Molecular Formula | C40H61N11O9 |
| Molecular Weight | Approximately 840.0 Da |
| C-Terminus | Lys-OH |
A Minimal Basic Extension beyond Leu-Enkephalin
Leu-enkephalin ends after Leu5. α-Neo-Endorphin (1-7) adds Arg6-Lys7, increasing positive charge while keeping the peptide substantially shorter than the native 10-residue sequence.
This makes it useful for dissecting the transition from a short enkephalin-like pharmacophore toward the longer prodynorphin-derived receptor-address architecture.
Comparison with α-Neoendorphin (1-8)
The corresponding 1-8 fragment adds Tyr8. Comparing the two peptides isolates the contribution of a single aromatic residue while keeping the remaining sequence unchanged.
Frequently Asked Questions
Does this peptide contain Tyr8?
No. It terminates at Lys7.
What is the N-terminal opioid motif?
The first five residues are Tyr-Gly-Gly-Phe-Leu, the Leu-enkephalin sequence.