[Tyr5,D-Trp6,8,9,Arg-NH210]-Neurokinin A (4-10) is a modified analog of the heptapeptide Neurokinin A (4-10), incorporating tyrosine (Tyr) at position 5, D-tryptophan (D-Trp) at positions 6, 8, and 9, and amidated arginine (Arg-NH₂) at position 10. These substitutions enhance stability, resistance to enzymatic degradation, and binding specificity for neurokinin-2 (NK-2) receptors. Retaining bioactivity, it modulates inflammatory responses, immune functions, and cardiovascular regulation. Utilized in pharmacological research, this analog serves as a tool to investigate structure-activity relationships, receptor activation mechanisms, and explore therapeutic potential for inflammatory disorders and cardiovascular diseases.

Chemical Formula: C57H68N14O10

Molecular Weight: 1109.30

Sequence: Asp-Tyr-D-Trp-Val-D-Trp-D-Trp-Arg-NH2

Purity: From crude to 98%

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