[Tyr0]-Neurokinin B is a modified analog of Neurokinin B with tyrosine (Tyr) substituted at position 0 (N-terminal), replacing the native histidine (His). This modification enhances stability, resistance to enzymatic degradation, and binding specificity for neurokinin-3 (NK-3) receptors. Retaining bioactivity, it modulates pain signaling, inflammatory responses, and cardiovascular regulation. Utilized in pharmacological research, this analog serves as a tool to investigate structure-activity relationships, receptor activation mechanisms, and explore therapeutic potential for pain management, inflammatory disorders, and cardiovascular conditions.

Chemical Formula: C64H88N14O16S2

Molecular Weight: 1373.63

Sequence: Tyr-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2

Purity: From crude to 98%

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Research Use Only