α-Endorphin is an endogenous opioid neuropeptide derived from the pro-opiomelanocortin (POMC) precursor, consisting of 16 amino acids. It acts as a ligand for μ, δ, and κ opioid receptors, mediating analgesia, mood regulation, and immune modulation. This peptide plays a critical role in pain perception, stress responses, and gastrointestinal motility. In pharmacological research, α-Endorphin serves as a tool to study opioid receptor activation mechanisms, structure-activity relationships, and the development of analgesic and anti-addiction therapies. Its natural origin and receptor specificity underscore its significance in understanding endogenous pain modulation and psychiatric disorders.

Chemical Formula: C77H120N18O26S

Molecular Weight: 1745.98

Sequence: Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr

Purity: From crude to 98%

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