Substance P, Free Acid is a modified form of the neuropeptide Substance P, lacking the C-terminal amidation (NH₂ group). This variant is often used in biochemical research to study the structural requirements for receptor binding and signaling, as the absence of amidation typically reduces or abolishes its biological activity. It serves as a critical tool for understanding peptide stability, metabolism, and the role of post-translational modifications in neuropeptide function.

Chemical Formula: C63H97N17O14S

Molecular Weight: 1348.65

Sequence: Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met

Purity: From crude to 98%

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Research Use Only