[Met5, Lys6, Arg7] α-Neo-Endorphin (1-7) is a modified analog of the opioid peptide α-Neo-Endorphin (1-7), incorporating methionine (Met) at position 5, lysine (Lys) at position 6, and arginine (Arg) at position 7. These substitutions enhance stability, resistance to enzymatic degradation, and binding specificity for μ, δ, and κ opioid receptors. Retaining bioactivity, it mediates analgesic effects, mood regulation, and immune modulation. In pharmacological research, this analog serves as a tool to investigate opioid receptor activation mechanisms, structure-activity relationships, and explore therapeutic potential for pain management, addiction therapies, and psychiatric disorders. Its truncated form and amino acid substitutions enable focused studies on receptor specificity and peptide-drug development.

Chemical Formula: C39H59N11O9S

Molecular Weight: 858.04

Sequence: Tyr-Gly-Gly-Phe-Met-Lys-Arg

Purity: From crude to 98%

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Research Use Only