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(S)-Benzyl 2-amino-6-((tert-butoxycarbonyl)amino)hexanoate hydrochloride (CAS 133170-57-7) is a Protected amino-acid / amino-ester intermediate selected for selective functionalization, ester chemistry and route development. This positions it within solution-phase synthesis and protected amino-acid derivatization.
Check which functional group remains available before substituting it for a conventional SPPS monomer; protection pattern defines the usable reaction handle. Procurement should match the exact CAS, protection state and lot-specific analytical specification to the intended route.
Product Information
| Product Name | (S)-Benzyl 2-amino-6-((tert-butoxycarbonyl)amino)hexanoate hydrochloride |
| Catalog No. | AS4211 |
| CAS No. | 133170-57-7 |
| Molecular Formula | C18H29ClN2O4 |
| Molecular Weight | 372.89 g/mol |
| Compound Type | Protected amino-acid / amino-ester intermediate |
| Primary Research Use | Solution-phase synthesis and protected amino-acid derivatization |
Protection Pattern and Synthetic Role
(S)-Benzyl 2-amino-6-((tert-butoxycarbonyl)amino)hexanoate hydrochloride combines an amino-acid framework with selective protection or esterification. The practical role is determined by which amino, carboxyl or side-chain functions remain free for the next transformation.
Solution-Phase and Derivatization Use
Such intermediates are useful in stepwise small-molecule synthesis, protected peptide-fragment preparation and route development where orthogonality is more important than direct compatibility with a single standard SPPS cycle.
Selection Considerations
Do not substitute one protected amino-acid form for another based only on the parent residue name. The ester, N-protecting group, salt form and side-chain protection change reactivity and deprotection sequence.
Browse the unusual residue building blocks for related structures. Complex sequence work can also use specialty peptide building blocks.
Product Documents
MSDS - (S)-Benzyl 2-amino-6-((tert-butoxycarbonyl)amino)hexanoate hydrochloride (AS4211)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
What is (S)-Benzyl 2-amino-6-((tert-butoxycarbonyl)amino)hexanoate hydrochloride mainly used for?
Solution-phase synthesis and protected amino-acid derivatization.
What is the critical identity check?
Confirm CAS 133170-57-7, stereochemistry or positional isomer where applicable, and the complete protection state.
What documentation should be matched to the lot?
Use the COA to confirm assay and analytical identity; the nominal formula is C18H29ClN2O4 with molecular weight 372.89 g/mol.