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Home Product Protected Amino Acids, Resins & Reagents Specialty Peptide Building Blocks (R)-2-[(9H-Fluoren-9-ylmethoxycarbonylamino)-Methyl]-Butyric Acid

DESCRIPTION

Fmoc-R-AMBA-OH (CAS 1217711-57-3) is a Protected amino-acid / peptidomimetic building block selected for a noncanonical or specially protected residue used to expand peptide and small-molecule chemical space. This positions it within peptide, peptidomimetic and medicinal-chemistry synthesis.

Use when the target structure specifically requires this residue or protection pattern; confirm stereochemistry and deprotection compatibility before substituting it into an established route. The most relevant purchasing decision is whether this exact derivative removes a known synthetic constraint in the planned sequence or small-molecule route.

Product Information

Product NameFmoc-R-AMBA-OH
Catalog No.AS4207
CAS No.1217711-57-3
Molecular FormulaC20H21NO4
Molecular Weight339.39 g/mol
Compound TypeProtected amino-acid / peptidomimetic building block
Primary Research UsePeptide, peptidomimetic and medicinal-chemistry synthesis

Functional Role of the Residue

Fmoc-R-AMBA-OH provides a noncanonical or specially protected residue used to expand peptide and small-molecule chemical space. In a peptide or small-molecule route, this feature should be introduced deliberately because it can change both synthetic behavior and final molecular properties.

Route Compatibility

Evaluate coupling conditions and deprotection orthogonality with the neighboring residues and other protecting groups already present. The most reliable route is the one designed around the full protection pattern, not an isolated building block.

Browse the unusual residue building blocks for related structures. Complex sequence work can also use specialty peptide building blocks.

Product Documents

MSDS - Fmoc-R-AMBA-OH (AS4207)

The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.

Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.

Frequently Asked Questions

Why does the exact derivative matter?

Fmoc-R-AMBA-OH is selected for its defined functional groups and protection pattern; related forms can require different coupling or deprotection conditions.

Can a close analog replace Fmoc-R-AMBA-OH?

Not safely by name alone. For Fmoc-R-AMBA-OH, compare stereochemistry, protecting groups, salt/ester form and the intended downstream transformation.

What should procurement verify?

Match the product to CAS 1217711-57-3 and the lot-specific COA rather than relying only on a shorthand chemical name.

Research Use Only.

(R)-2-[(9H-Fluoren-9-ylmethoxycarbonylamino)-Methyl]-Butyric Acid

Catalog No: AS4207
Cas No: 1217711-57-3

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