$673.00 - $2020.00
L-Lysine methyl ester diHCl (CAS 26348-70-9) is a Protected amino-acid / amino-ester intermediate used in solution-phase synthesis and protected amino-acid derivatization. Its main synthetic value is selective functionalization, ester chemistry and route development.
Check which functional group remains available before substituting it for a conventional SPPS monomer; protection pattern defines the usable reaction handle. For reproducible work, confirm identity and protection state against the COA before transferring conditions from a related analog.
Product Information
| Product Name | L-Lysine methyl ester diHCl |
| Catalog No. | AS4259 |
| CAS No. | 26348-70-9 |
| Molecular Formula | C7H18Cl2N2O2 |
| Molecular Weight | 233.14 g/mol |
| Compound Type | Protected amino-acid / amino-ester intermediate |
| Primary Research Use | Solution-phase synthesis and protected amino-acid derivatization |
Protection Pattern and Synthetic Role
L-Lysine methyl ester diHCl combines an amino-acid framework with selective protection or esterification. The practical role is determined by which amino, carboxyl or side-chain functions remain free for the next transformation.
Solution-Phase and Derivatization Use
Such intermediates are useful in stepwise small-molecule synthesis, protected peptide-fragment preparation and route development where orthogonality is more important than direct compatibility with a single standard SPPS cycle.
Selection Considerations
Do not substitute one protected amino-acid form for another based only on the parent residue name. The ester, N-protecting group, salt form and side-chain protection change reactivity and deprotection sequence.
Related options are grouped under unusual amino acid range. For broader route support, see advanced peptide building blocks.
Product Documents
MSDS - L-Lysine methyl ester diHCl (AS4259)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
Why does the exact derivative matter?
L-Lysine methyl ester diHCl is selected for its defined functional groups and protection pattern; related forms can require different coupling or deprotection conditions.
Can a close analog replace L-Lysine methyl ester diHCl?
Not safely by name alone. For L-Lysine methyl ester diHCl, compare stereochemistry, protecting groups, salt/ester form and the intended downstream transformation.
What should procurement verify?
Match the product to CAS 26348-70-9 and the lot-specific COA rather than relying only on a shorthand chemical name.