gp100 (178 - 187) is a 10 - amino - acid peptide sequence sourced from the glycoprotein 100 (gp100), a protein prominently expressed by melanoma cells. This particular fragment serves as a crucial antigenic determinant. It has the ability to bind to major histocompatibility complex (MHC) class I molecules on the surface of antigen - presenting cells. Once presented in this context, it can be recognized by cytotoxic T lymphocytes (CTLs). In melanoma immunotherapy, gp100 (178 - 187) holds significant promise. It can be used to design vaccines that aim to activate the immune system, specifically CTLs, to target and eliminate melanoma cells. Scientists study how to enhance the peptide's immunogenic potential, its optimal presentation by MHC molecules, and how to boost the CTL - mediated cytotoxic response against melanoma, all with the goal of improving the outcomes of immunotherapeutic strategies for this type of cancer.

Chemical Formula: C42H71N11O14S2

Molecular Weight: 1018.23

Sequence: Met-Leu-Gly-Thr-His-Thr-Met-Glu-Val

Purity: From crude to 98%

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