Gastrin Releasing Peptide, porcine is a 27-amino acid neuropeptide belonging to the bombesin family, naturally occurring in pigs and involved in regulating gastrointestinal (GI) function. Similar to its human counterpart, porcine gastrin-releasing peptide (GRP) acts as a key mediator in the GI tract, stimulating gastrin release from gastric G cells to promote hydrochloric acid secretion, mucosal cell growth, and GI motility. It binds to gastrin-releasing peptide receptors (GRPR), initiating signaling pathways that govern digestive processes and cell proliferation. In research, this peptide serves as a valuable tool for studying species-specific GRPR interactions, comparative GI physiology, and receptor-mediated signaling in porcine models, which are widely used in veterinary medicine and translational studies. Its role in regulating gastric function makes it essential for understanding digestive health and exploring therapeutic strategies for disorders affecting the porcine GI system.

Chemical Formula: C126H198N38O31S2

Molecular Weight: 2805.40

Sequence: Ala-Pro-Val-Ser-Val-Gly-Gly-Gly-Thr-Val-Leu-Ala-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2

Purity: From crude to 98%

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Research Use Only