$108.00 - $554.00
Fmoc-TTDS-OH (CAS 172089-14-4) is an Fmoc-protected hydrophilic spacer selected for hydrophilic spacing, conjugation and distance control. This positions it within linker installation in peptide and bioconjugate synthesis.
Choose when a flexible polar spacer is needed between a peptide and a label, ligand or other functional group. Procurement should match the exact CAS, protection state and lot-specific analytical specification to the intended route.
Product Information
| Product Name | Fmoc-TTDS-OH |
| Catalog No. | AS4231 |
| CAS No. | 172089-14-4 |
| Molecular Formula | C29H38N2O8 |
| Molecular Weight | 542.62 g/mol |
| Compound Type | Fmoc-protected hydrophilic spacer |
| Primary Research Use | Linker installation in peptide and bioconjugate synthesis |
Hydrophilic Spacer Design
Fmoc-TTDS-OH is used as an Fmoc-protected spacer building block when additional distance and polarity are required between a peptide and a conjugated group. Linker choice can influence solubility, steric access and presentation of the attached functionality.
Incorporation Strategy
The Fmoc-protected amine is compatible with stepwise assembly strategies while the carboxyl group provides the coupling point. The linker should be positioned according to the desired orientation of the final conjugate.
Selection Considerations
Spacer length should be selected from the biological or analytical geometry of the final construct rather than from solubility alone. Compare linker length, polarity and terminal functionality before substitution.
Browse the small-molecule building blocks for related structures. Complex sequence work can also use difficult peptide synthesis.
Product Documents
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
Why does the exact derivative matter?
Fmoc-TTDS-OH is selected for its defined functional groups and protection pattern; related forms can require different coupling or deprotection conditions.
Can a close analog replace Fmoc-TTDS-OH?
Not safely by name alone. For Fmoc-TTDS-OH, compare stereochemistry, protecting groups, salt/ester form and the intended downstream transformation.
What should procurement verify?
Match the product to CAS 172089-14-4 and the lot-specific COA rather than relying only on a shorthand chemical name.