$28.57 - $85.71
Fmoc-(R)-3-aminoisobutyric acid (CAS 211682-15-4) is supplied as a Protected amino-acid / peptidomimetic building block. In research synthesis, it is most relevant to peptide, peptidomimetic and medicinal-chemistry synthesis and a homologated or beta-amino-acid framework that changes backbone spacing and conformational preferences.
Use when the target structure specifically requires this residue or protection pattern; confirm stereochemistry and deprotection compatibility before substituting it into an established route. The most relevant purchasing decision is whether this exact derivative removes a known synthetic constraint in the planned sequence or small-molecule route.
Product Information
| Product Name | Fmoc-(R)-3-aminoisobutyric acid |
| Catalog No. | AS4252 |
| CAS No. | 211682-15-4 |
| Molecular Formula | C19H19NO4 |
| Molecular Weight | 325.36 g/mol |
| Compound Type | Protected amino-acid / peptidomimetic building block |
| Primary Research Use | Peptide, peptidomimetic and medicinal-chemistry synthesis |
Application in Peptide and Peptidomimetic Design
Fmoc-(R)-3-aminoisobutyric acid expands accessible chemical space through a homologated or beta-amino-acid framework that changes backbone spacing and conformational preferences. This makes the product most relevant to sequence-defined SAR, conformational studies or specialized synthetic targets.
What to Check Before Incorporation
Confirm stereochemistry, free versus protected functional groups and the planned cleavage sequence. These details affect activation choice, solubility and the identity of the final residue.
Procurement Relevance
Use CAS 211682-15-4 together with the full product name when comparing suppliers. Similar shorthand names can refer to different positional isomers or protection states.
Additional chemistry is available in the specialty amino acid set. For synthesis planning beyond the building block, see specialty SPPS building blocks.
Product Documents
MSDS - Fmoc-(R)-3-aminoisobutyric acid (AS4252)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
Why does the exact derivative matter?
Fmoc-(R)-3-aminoisobutyric acid is selected for its defined functional groups and protection pattern; related forms can require different coupling or deprotection conditions.
Can a close analog replace Fmoc-(R)-3-aminoisobutyric acid?
Not safely by name alone. For Fmoc-(R)-3-aminoisobutyric acid, compare stereochemistry, protecting groups, salt/ester form and the intended downstream transformation.
What should procurement verify?
Match the product to CAS 211682-15-4 and the lot-specific COA rather than relying only on a shorthand chemical name.