$224.00 - $2020.00
Fmoc-Asp(OMpe)-OH (CAS 180675-08-5) belongs to the protected amino-acid / peptidomimetic building block class. It is used in peptide, peptidomimetic and medicinal-chemistry synthesis, particularly where an acidic amino-acid derivative with ester protection used to control carboxyl-group reactivity is required.
Use when the target structure specifically requires this residue or protection pattern; confirm stereochemistry and deprotection compatibility before substituting it into an established route. For reproducible work, confirm identity and protection state against the COA before transferring conditions from a related analog.
Product Information
| Product Name | Fmoc-Asp(OMpe)-OH |
| Catalog No. | AS4233 |
| CAS No. | 180675-08-5 |
| Molecular Formula | C25H29NO6 |
| Molecular Weight | 439.50 g/mol |
| Compound Type | Protected amino-acid / peptidomimetic building block |
| Primary Research Use | Peptide, peptidomimetic and medicinal-chemistry synthesis |
Why This Building Block Is Distinct
The defining feature of Fmoc-Asp(OMpe)-OH is an acidic amino-acid derivative with ester protection used to control carboxyl-group reactivity. That feature can change hydrophobic packing, conformational preference, side-chain reactivity or the route available for later derivatization.
Coupling and Deprotection Fit
Compatibility should be assessed against the full sequence and protection map. A chemically correct residue can still be a poor substitution if its protecting group is removed by conditions required elsewhere in the synthesis.
Compare neighboring reagents in our noncanonical amino acids. Full-sequence work is covered under protected peptide building blocks.
Product Documents
MSDS - Fmoc-Asp(OMpe)-OH (AS4233)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
What distinguishes Fmoc-Asp(OMpe)-OH in synthesis?
Its intended role is peptide, peptidomimetic and medicinal-chemistry synthesis, with the exact residue or functional-group state defined by the product structure.
Why check the protection map for Fmoc-Asp(OMpe)-OH?
In Fmoc-Asp(OMpe)-OH, the protection state determines which functions remain reactive and which deprotection conditions can be used later in the route.