Exendin 4 (Glu1) is a synthetic 39-amino acid peptide analog of Exendin 4, featuring a glutamic acid (Glu) substitution at the N-terminal position 1 (wild-type Exendin 4 has histidine, His). This modification alters the peptide’s structure while retaining the core GLP-1 receptor-binding domain. It serves as a tool to investigate the impact of N-terminal residues on GLP-1 receptor activation, ligand stability, and pharmacokinetic properties.

Chemical Formula: C176H272N46O58S

Molecular Weight: 3992.47

Sequence: Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Purity: From crude to 98%

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Research Use Only