Exendin 4 is a 39-amino acid peptide derived from the saliva of the Gila monster (Heloderma suspectum), acting as a potent agonist of the glucagon-like peptide-1 (GLP-1) receptor. It mimics native GLP-1’s effects by stimulating glucose-dependent insulin secretion, inhibiting glucagon release, and delaying gastric emptying. Widely used in diabetes and obesity research, it serves as a foundational tool for developing GLP-1 receptor-based therapies.

Chemical Formula: C184H282N50O60S1

Molecular Weight: 4186.03

Sequence: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Purity: From crude to 98%

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Research Use Only