$117.00 - $340.00
Boc-Gln-Gln-OH is a preassembled L-glutamine-L-glutamine dipeptide with N-terminal Boc protection and a free C-terminal carboxyl group. It can be introduced as a defined Gln-Gln fragment instead of constructing the two-residue motif one coupling cycle at a time.
We recommend choosing this fragment because it solves a defined route problem, not simply because fewer steps sound preferable. For short, routine peptides, direct SPPS may be simpler. For repeated Gln-Gln motifs or solution-phase fragment work, a verified dipeptide can improve route control and reduce one deletion opportunity.
Product Information
| Product Name | Boc-Gln-Gln-OH |
| Catalog No. | AS4047 |
| CAS No. | 250290-76-7 |
| Molecular Formula | C15H26N4O7 |
| Molecular Weight | 374.39 g/mol |
| Chemical Identity | Boc-L-Gln-L-Gln-OH |
| Primary Applications | Protected-fragment synthesis, Gln-rich peptide assembly and solution-phase coupling |
When a preformed Gln-Gln fragment is useful
Gln-rich sequences can become difficult as chain length increases because polarity, hydrogen bonding and aggregation can complicate coupling and purification. A preformed dipeptide does not solve every sequence-level problem, but it reduces one coupling step and lets the Gln-Gln bond be characterized before the fragment enters a longer route.
Protection and downstream assembly
The Boc group protects the N-terminal amine and is acid-labile. The C-terminal carboxyl remains available for activation. Route planning should consider whether the broader synthesis uses Boc-compatible conditions and whether a fragment-coupling strategy offers an advantage over standard residue-by-residue SPPS.
Procurement and QC Considerations
Confirm CAS 250290-76-7, the stated molecular formula and lot-specific analytical identity. Review the COA together with the MSDS when the material will be used in sequence-sensitive or process-development work.
Product Documents
A Safety Data Sheet (SDS / MSDS) is available for this product to support laboratory handling, storage and safety assessment.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
What is Boc-Gln-Gln-OH used for?
It is used as a protected Gln-Gln dipeptide fragment for peptide assembly and research synthesis.
Does it eliminate aggregation in Gln-rich peptides?
No. It can reduce a coupling step, but aggregation and solubility depend on the complete sequence.
Is the C-terminus available for coupling?
Yes. The product has a free C-terminal carboxyl group.
Related Technical Resources
Browse related specialty peptide building blocks for protected amino acids, fragments and noncanonical synthesis intermediates.
For complete sequence work using this chemistry, see our protected-fragment peptide synthesis.