$1538.00 - $4615.00
Boc-D-Orn(Boc)-OH (CAS 137524-82-4) is a Protected amino-acid / peptidomimetic building block used in peptide, peptidomimetic and medicinal-chemistry synthesis. Its main synthetic value is the D-ornithine diamino-acid framework with both the α-amino and side-chain amino groups protected as Boc derivatives.
Use when the target structure specifically requires this residue or protection pattern; confirm stereochemistry and deprotection compatibility before substituting it into an established route. For reproducible work, confirm identity and protection state against the COA before transferring conditions from a related analog.
Product Information
| Product Name | Boc-D-Orn(Boc)-OH |
| Catalog No. | AS4218 |
| CAS No. | 137524-82-4 |
| Molecular Formula | C15H28N2O6 |
| Molecular Weight | 332.39 g/mol |
| Compound Type | Protected amino-acid / peptidomimetic building block |
| Primary Research Use | Peptide, peptidomimetic and medicinal-chemistry synthesis |
Residue Design and Application
Boc-D-Orn(Boc)-OH is useful when D-ornithine stereochemistry and temporary protection of both amino groups are required. Because both the α-amino and side-chain amino functions are Boc-protected, this derivative does not provide orthogonal deprotection between the two nitrogens; route design should account for their shared acid-labile protection chemistry.
Protection Strategy
The dual Boc protection suppresses both amino groups during the relevant synthetic steps. Deprotection is acid-mediated, so removal of the two Boc groups should not be treated as an inherently selective or orthogonal operation. Confirm compatibility with other acid-sensitive groups in the complete route.
Sequence-Level Decision
Use this derivative when its side chain, backbone spacing or stereochemistry is part of the design hypothesis. For routine sequences, the corresponding standard residue is usually the simpler choice.
Related options are grouped under unusual amino acid range. For broader route support, see advanced peptide building blocks.
Product Documents
MSDS - Boc-D-Orn(Boc)-OH (AS4218)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
What distinguishes Boc-D-Orn(Boc)-OH in synthesis?
Its intended role is peptide, peptidomimetic and medicinal-chemistry synthesis, with the exact residue or functional-group state defined by the product structure.
Why check the protection map for Boc-D-Orn(Boc)-OH?
In Boc-D-Orn(Boc)-OH, the protection state determines which functions remain reactive and which deprotection conditions can be used later in the route.