β-Interleukin II (44-56) is an 13-amino-acid peptide fragment derived from the human Interleukin-2 (IL-2) cytokine, corresponding to residues 44–56 of its primary structure. IL-2 is a critical regulator of T-cell activation, proliferation, and immune response, and this segment is located within a region involved in receptor binding (IL-2Rα/β/γ complexes). The fragment retains the ability to interact with IL-2 receptor subunits, modulating signaling pathways that drive lymphocyte differentiation and cytokine production. In pharmacological research, β-Interleukin II (44-56) serves as a tool to investigate IL-2 receptor recognition mechanisms, structure-activity relationships, and the development of targeted immunomodulators. It supports studies on T-cell-mediated immunity, cancer immunotherapy, and autoimmune disorders, offering insights into how peptide fragments can enhance or inhibit IL-2 signaling for therapeutic purposes.

Chemical Formula: C68H113N19O19

Molecular Weight: 1500.77

Sequence: Ile-Leu-Asn-Gly-Ile-Asn-Asn-Tyr-Lys-Asn-Pro-Lys-Leu

Purity: From crude to 98%

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Research Use Only