[Arg8]-α-Neo-Endorphin (1-8) is a modified analog of the opioid peptide α-Neo-Endorphin (1-8), with arginine (Arg) substituted at position 8. This modification enhances stability, resistance to enzymatic degradation, and binding affinity for μ, δ, and κ opioid receptors. Retaining bioactivity, it mediates analgesic effects, mood regulation, and immune modulation. In pharmacological research, this analog serves as a tool to investigate opioid receptor activation mechanisms, structure-activity relationships, and explore therapeutic potential for pain management, addiction therapies, and psychiatric disorders. Its truncated form and Arg substitution enable focused studies on receptor specificity and peptide-drug development.

Chemical Formula: C46H73N15O10

Molecular Weight: 996.19

Sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Arg

Purity: From crude to 98%

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Research Use Only