Angiotensin Converting Enzyme Inhibitor (ACE Inhibitor) is a class of pharmacological agents that block the activity of angiotensin-converting enzyme (ACE), an enzyme critical for the renin-angiotensin-aldosterone system (RAAS). By inhibiting ACE, these compounds prevent the conversion of angiotensin I to the potent vasoconstrictor angiotensin II, reducing vascular tone, aldosterone secretion, and sodium retention, while also increasing levels of the vasodilatory peptide bradykinin (by inhibiting its degradation). Clinically, ACE Inhibitors are widely used to treat hypertension, heart failure, diabetic nephropathy, and post-myocardial infarction, as they improve cardiovascular function, reduce blood pressure, and protect renal integrity. In pharmacological research, they serve as tools to investigate RAAS signaling, bradykinin-mediated pathways, and the role of ACE in inflammation and fibrosis. Common examples include captopril, enalapril, and lisinopril, highlighting their versatility in managing diverse cardiovascular and renal disorders by targeting both vasoconstrictive and vasodilatory mechanisms.

Chemical Formula: C53H77N14O12

Molecular Weight: 1102.29

Sequence: Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro

Purity: From crude to 98%

If there are no products available iwth the required purity and quantity, please inform us of your specifications and send an email to sales@alanscientific.com

Our representitives will respond within 24 hours

Research Use Only