Ac-Gly-Trp-NH2 is N-acetyl-Gly-Trp-amide with an N-acetyl group and C-terminal amide. The blocked termini reduce terminal-charge effects and make the compound useful as a compact model of an internal peptide environment.

Product Information

Application as a Capped Peptide Model

Terminal capping makes Ac-Gly-Trp-NH2 more representative of an internal peptide segment than the corresponding free amino acid or uncapped dipeptide. The tryptophan side chain provides the main product-specific chemical feature for comparative physicochemical or analytical work.

Lot Documentation and Sample Handling

For comparative or quantitative studies, review the lot-specific purity method together with molecular identity data. HPLC purity, mass confirmation and nominal vial mass describe different attributes and should not be treated as equivalent measures of analyte content.

For oxidation-sensitive experiments, baseline oxidized impurities and solution history should be controlled. Solvent and working concentration should be validated for the intended assay when no product-specific solution data are supplied.

Related capped models can be explored under peptide model compounds.

Product Documents

MSDS - Ac-Gly-Trp-NH2 (AS4124)

The Safety Data Sheet provides product identification, laboratory handling guidance, exposure controls, transport information and safety information for research use.

Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.

Frequently Asked Questions

Are both termini blocked?

Yes. The N-terminus is acetylated and the C-terminus is amidated.

Can this material be treated as an ordinary chain-extension reagent?

No. The capped termini make it better suited to model, analytical or assay applications than routine peptide elongation.

Research Use Only.