$103.00 - $310.00
(3S)-Fmoc-3-amino-1-carboxymethyl-valerolactame (CAS 215190-25-3) belongs to the protected amino-acid / peptidomimetic building block class. It is used in peptide, peptidomimetic and medicinal-chemistry synthesis, particularly where a conformationally constrained backbone framework for structure-focused peptide design is required.
Use when the target structure specifically requires this residue or protection pattern; confirm stereochemistry and deprotection compatibility before substituting it into an established route. For reproducible work, confirm identity and protection state against the COA before transferring conditions from a related analog.
Product Information
| Product Name | (3S)-Fmoc-3-amino-1-carboxymethyl-valerolactame |
| Catalog No. | AS4253 |
| CAS No. | 215190-25-3 |
| Molecular Formula | C22H22N2O5 |
| Molecular Weight | 394.42 g/mol |
| Compound Type | Protected amino-acid / peptidomimetic building block |
| Primary Research Use | Peptide, peptidomimetic and medicinal-chemistry synthesis |
Why This Building Block Is Distinct
The defining feature of (3S)-Fmoc-3-amino-1-carboxymethyl-valerolactame is a conformationally constrained backbone framework for structure-focused peptide design. That feature can change hydrophobic packing, conformational preference, side-chain reactivity or the route available for later derivatization.
Coupling and Deprotection Fit
Compatibility should be assessed against the full sequence and protection map. A chemically correct residue can still be a poor substitution if its protecting group is removed by conditions required elsewhere in the synthesis.
Compare neighboring reagents in our noncanonical amino acids. Full-sequence work is covered under protected peptide building blocks.
Product Documents
MSDS - (3S)-Fmoc-3-amino-1-carboxymethyl-valerolactame (AS4253)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
What is (3S)-Fmoc-3-amino-1-carboxymethyl-valerolactame mainly used for?
Peptide, peptidomimetic and medicinal-chemistry synthesis.
What is the critical identity check?
Confirm CAS 215190-25-3, stereochemistry or positional isomer where applicable, and the complete protection state.
What documentation should be matched to the lot?
Use the COA to confirm assay and analytical identity; the nominal formula is C22H22N2O5 with molecular weight 394.42 g/mol.