$1206.00 - $3618.00
Fmoc-DL-Pro-OH (CAS 144829-96-9) is supplied as a Protected amino-acid / peptidomimetic building block. In research synthesis, it is most relevant to peptide, peptidomimetic and medicinal-chemistry synthesis and a noncanonical or specially protected residue used to expand peptide and small-molecule chemical space.
Use when the target structure specifically requires this residue or protection pattern; confirm stereochemistry and deprotection compatibility before substituting it into an established route. Its value is route-specific, so selection should follow the intended transformation rather than the broad category label.
Product Information
| Product Name | Fmoc-DL-Pro-OH |
| Catalog No. | AS4220 |
| CAS No. | 144829-96-9 |
| Molecular Formula | C20H19NO4 |
| Molecular Weight | 337.37 g/mol |
| Compound Type | Protected amino-acid / peptidomimetic building block |
| Primary Research Use | Peptide, peptidomimetic and medicinal-chemistry synthesis |
Application in Peptide and Peptidomimetic Design
Fmoc-DL-Pro-OH expands accessible chemical space through a noncanonical or specially protected residue used to expand peptide and small-molecule chemical space. This makes the product most relevant to sequence-defined SAR, conformational studies or specialized synthetic targets.
What to Check Before Incorporation
Confirm stereochemistry, free versus protected functional groups and the planned cleavage sequence. These details affect activation choice, solubility and the identity of the final residue.
Procurement Relevance
Use CAS 144829-96-9 together with the full product name when comparing suppliers. Similar shorthand names can refer to different positional isomers or protection states.
Additional chemistry is available in the specialty amino acid set. For synthesis planning beyond the building block, see specialty SPPS building blocks.
Product Documents
MSDS - Fmoc-DL-Pro-OH (AS4220)
The Safety Data Sheet provides product identification, hazard information, handling and storage guidance, exposure controls, transport information, and regulatory information for laboratory use.
Certificates of Analysis (COAs) are batch-specific. Please contact us to request the COA for your product, and we will provide it by email.
Frequently Asked Questions
What is Fmoc-DL-Pro-OH mainly used for?
Peptide, peptidomimetic and medicinal-chemistry synthesis.
What is the critical identity check?
Confirm CAS 144829-96-9, stereochemistry or positional isomer where applicable, and the complete protection state.
What documentation should be matched to the lot?
Use the COA to confirm assay and analytical identity; the nominal formula is C20H19NO4 with molecular weight 337.37 g/mol.