Orexin B, canine is an endogenous neuropeptide produced in the hypothalamus of dogs, consisting of 33 amino acids with high structural conservation across mammalian species. It acts as a ligand for Orexin 1 (OX1) and Orexin 2 (OX2) receptors, mediating critical roles in arousal, appetite regulation, energy homeostasis, and stress responses in canines. This peptide plays a central role in sleep-wake cycles, feeding behavior, and metabolic regulation in dogs. In pharmacological research, canine Orexin B serves as a tool to investigate receptor activation mechanisms, structure-activity relationships, and explore therapeutic potential for disorders like insomnia, narcolepsy, and obesity in veterinary medicine. Its cross-species conservation also contributes to translational studies, offering insights into Orexin signaling pathways and drug development for both canine and human health.

Chemical Formula: C125H214N44O34S

Molecular Weight: 2909.44

Sequence: Arg-Pro-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2

Purity: From crude to 98%

If there are no products available iwth the required purity and quantity, please inform us of your specifications and send an email to sales@alanscientific.com

Our representitives will respond within 24 hours

Research Use Only