Octreotide Acetate is a synthetic octapeptide analog of somatostatin, designed to mimic the hormone’s ability to inhibit the secretion of growth hormone, insulin, glucagon, and other peptides. Composed of eight amino acids, it binds to somatostatin receptors with high affinity, particularly receptors subtype 2 and 5, to regulate hormonal activity and reduce tumor cell proliferation. Clinically, it is used to treat acromegaly (excessive growth hormone production), carcinoid syndrome (symptoms from neuroendocrine tumors), and diarrhea associated with VIPomas (vasoactive intestinal peptide-secreting tumors). Administered via subcutaneous injection or long-acting depot formulations, Octreotide Acetate effectively controls symptoms such as flushing, diarrhea, and tumor-related hormonal excess, while also slowing tumor growth in certain neuroendocrine cancers. Its synthetic nature and targeted action make it a critical tool in managing hormone-dependent disorders and malignancies.
Chemical Formula: C49H66N10O10S2
Molecular Weight: 1019.20
Sequence: D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-Ol(Disulfidebridge:Cys2-Cys7)
Purity: From crude to 98%
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