Melanotan II（MT-II） is a synthetic peptide analog of α-melanocyte-stimulating hormone (α-MSH), designed to activate melanocortin receptors—particularly MC1R on melanocytes—to induce melanin production and skin pigmentation. This non-selective agonist mimics the natural tanning process by stimulating the synthesis of eumelanin, leading to a darker skin tone, and is primarily used in research for its potential in photoprotection, treating skin disorders (e.g., vitiligo), or as a tanning agent. While studied for its ability to enhance UV resistance and reduce sunburn risk, Melanotan II is not approved for medical use in many regions due to safety concerns, including potential side effects like nausea, appetite suppression, or cardiovascular impacts. Its synthetic nature and melanogenic properties make it a subject of interest in cosmetic and biomedical research, though its use remains experimental and regulated due to unresolved risks and off-target effects.

Chemical Formula: C50H69N15O9

Molecular Weight: 1024.20

Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2(LactambridgeAsp2-Lys7)

Purity: From crude to 98%

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