HIV-1 tat Protein (47-57) is an 11 - amino acid peptide segment from the HIV-1 trans - activator of transcription (tat) protein. This region is highly conserved and contains a basic amino acid - rich motif, often referred to as the arginine - rich motif (ARM). It plays a pivotal role in HIV-1 replication by binding to the trans - activation response (TAR) element on the viral RNA. This binding recruits host cell factors, like cyclin T1 and CDK9, which are essential for the transition from transcriptional initiation to elongation. In research, this peptide is used to study the molecular mechanisms of HIV-1 gene expression regulation. By understanding how this segment interacts with TAR and host factors, scientists aim to develop drugs that can disrupt this crucial step in the viral life cycle, offering potential new strategies for treating HIV - 1 infections and AIDS.

Chemical Formula: C64H118N32O14

Molecular Weight: 1559.86

Sequence: Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg

Purity: From crude to 98%

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