HIV-1 tat Protein (1-9) is a short, 9-amino acid peptide fragment derived from the trans - activator of transcription (tat) protein of the human immunodeficiency virus type 1 (HIV - 1). This N - terminal region of the tat protein plays a crucial role in the regulation of viral gene expression. It contains key residues that are involved in the recruitment of host cell factors necessary for efficient transcription elongation of the viral RNA. In research, this peptide is used to study the early events in HIV - 1 replication, specifically the interaction between the tat protein and cellular transcription machinery. Understanding how this short peptide segment functions can provide insights into potential therapeutic strategies to disrupt HIV - 1 gene expression and halt viral replication, which is vital for the development of new treatments against AIDS.
Chemical Formula: C43H168N10O17S
Molecular Weight: 1029.14
Sequence: Met-Asp-Pro-Val-Asp-Pro-Asn-Ile-Glu
Purity: From crude to 98%
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Research Use Only